The kickoff of the anti - vax movement is often date to the late nineties , when a now - retracted paper found on manipulated datafalsely linkedthe MMR vaccine to autism . But the anti - vax movement is far older than that — in fact , it ’s as old as vaccines themselves .
Many biotic community have valid reasons to be conservative of politics aesculapian mandates : theTuskegee syphilis experimentandforced sterilisation programsare just two of medicine ’s many moody moments . But some people ’s opposition to safe and effective vaccines stems from understanding that are a short more … well , silly . Here are the stories of eight of history ’s most misguided anti - vaxxers .
1. William Douglass (1691-1752)
In the early 1700s , Douglass was the only doctor in Boston with an literal degree in medicinal drug . That ’s probably why he felt so surefooted about bemock a novel method acting of preventing smallpox introduce by three improbable masses : Cotton Mather , a Puritan minister intimately remembered today for his further theSalem witch trials;Onesimus , an enslaved African man ; and Zabdiel Boylston , an apothecary and surgeonwithouta medical degree . Onesimus had taught the other two men about a common practice in his homeland , in which children were deliberately exposed to minor cases of smallpox by applying pus from an infected person into a scratch on their arms . The children would get gently nauseous , but ordinarily retrieve , and thereafter enjoyed lifelong immunity from the deadly scourge . Mather and Boylston were so impressed with the theme that they decided to essay it out in 1721 , when a variola epidemic hit Boston .
Douglass was less impressed . He wrote a serial of newspaper articles and pamphlets , callingMather “ a credulous vain preacher ” and Boylston “ ignorant ” and a “ grievous quack ” [ PDF ] . He did n’t bother to acknowledge Onesimus .
Douglass was n’t the only spouter of anti - vax view in Ithiel Town . James Franklin and his well - know young brother , Benjamin , published a newspaper that contained newspaper column , articles , and even poems lampoon the medical advance . Yet another individual threw a grenade through Mather ’s window recent one night with a note attached that read , “ Cotton Mather , you dog , beshrew you ! I ’ll inoculate you with this ” [ PDF ] . as luck would have it for Mather and his family , the grenade failed to burst .

Despite all the protest , it was Onesimus , Mather , and Boylston who won in the last . By the time the next smallpox epidemic hit Boston a decade later , Douglass had transformed from an anti - vaxxer to an inoculation buff who offered the practice to his own patient . Douglass had a variety of center after Boylston published detailed records and fatality rates that proved his new method was much safer than allowing oneself to catch variola naturally . The occasion twist out to be story ’s first major ( successful)use of medical statistic .
2. Benjamin Moseley (1742-1819)
Moseley was a rich , well - civilise , and extremely consider Dr. in Georgian England , best knownfor his investigation into new consumer product like coffee and sugar . Unfortunately , he proposed that coffeecuredheadaches , coughs , asthma , gouty arthritis , and kidney Stone , and was a neat counterpoison to opium addiction , while the idea that sugar causes cavities was an " one-time womanhood ’s germ - bear , to frighten children . ” His take on vaccinations was n’t much better .
In 1796 , Edward Jenner had taken Onesimus ’s conception and improved on it , express that by using pus from vaccinia instead of actual smallpox , patients receive the same unsusceptibility as before , but now without the risk of catching the more serious disease or take place it on to others . This new method acting , called vaccination after the Romance parole for cow , vacca , quickly caught on .
Of course , every unexampled discovery has its detractors , and Moseley was one of the loudest . He gave vaccination his own new figure , includingcowmania , cow - dung , and even bovine syphilis ( they did n’t catch on ) . Moseley published accounts of the hypothecate negative side essence of inoculation in numerous pamphlets and journal clause . According to him , they include whooping cough and insanity . He cite suppose suit studies of a cleaning woman whose fount " began to resemblethat of an ox , ” and a young male child who grew cow hair all over his body .

Like many anti - vaxxers today , Moseley speculated that the long - terminal figure result of inoculation might be even worse : “ Can any person say what may be the consequences of introducing [ … ] a bestial humour , into the human frame , after a long lapse of years ? Who knows , besides , what thought may get up , in the class of time ? ” He meant that women might require to have sex with moo-cow : “ owe to vaccinationthe British ladies might cast in the fields to receive the embrace of the bull . ”
It sound goofy , but Moseley was an early articulator of a still - vernacular feeling : that vaccines check something unnatural , dirty , or toxic that can infect our healthy trunk . We ’ve change the focus of this fear from cow pus to hydrargyrum or formaldehyde , but the underlying thought is at least 200 years old .
3. Ferdinand Smyth Stuart (1745-1814)
Stuart was a slap-up - grandson of King Charles II and called himself a doctor , though he probablydidn’tactually have a medical grade . He was also one of Moseley ’s loud jock . Adding to the word of advice about horny woman with motor horn , Stuart published a story of a young boy who change his behavior after vaccination : His “ former raw dispositionabsolutely changed to the brutal , so that it run upon all quatern like a wolf , bellowing like a cow , and butting like a strapper . ”
This pamphlet — which had the unbelievable title of£30,000 for the cow - pox ! ! ! An address to the British Parliament , on inoculation ( of the not bad grandness to mankind)—came with acover illustrationshowing Jenner and other pro - vaccination doctor tipping basket of babies into the oral cavity of a atrocious , seeping cow that ’s sick not only with cowpox , but with leprosy , plague , and ulcers . The deed referred to £ 30,000 that the British Parliament had recently granted Jenner as a reward for his discovery . Stuart , like many anti - vaxxers since , pointed to the money as a motivation for why “ thismonster[vaccination ] has found not only a throng of friends butworshippers , who bow down themselves before him , and boost his voracious appetite . ”
Stuart also pioneered the method acting of discredit vaccine by associating them with his political foeman . In this case , because he was British and writing in 1807 , his rant buy the farm after Britain ’s greatest enemy : the French . “ Are we to worship — to applaud — or even to state toEvil , toBuonaparté , or toVaccination , because they have for some time been well-heeled ? No ! Never let us disgrace our award , our moral excellence , or our consciences by such obsequiousness , " he wrote .
Speaking of Napoleon , he was an early adopter of inoculation — having had his firstborn son immunise even before he was baptized — and a huge fan of Dr. Jenner , once sayingafter Jenner had take for a favour , " Ah , Jenner , I can pass up him nothing . "
4. Jules Guérin (1801-1886)
Dr. Guérin ’s great adversary was Louis Pasteur , who became a global famous person for develop the first vaccines for diseases other than variola major , including rabies and anthrax . But at the time of the clash between Guérin and Pasteur , those breakthrough lay in the futurity . In 1880 , Pasteur had just presented his finding on his very first vaccinum ( to forbid chicken cholera ) to France ’s Académie Nationale de Médecine , only to be interrupted and mocked by Guérin . He require Pasteur over and over to excuse how he had made the vaccinum , and then pretended not to understand the explanations . He mocked Pasteur for not being a real Dr. ( Pasteur had two doctorates in chemistry and physics , but never received a aesculapian stage ) . Guérincaused such chaosthat the meeting ended early . When the Académie meet again a hebdomad later , Pasteur announce that he would never “ respond to the indiscreet , heavy , and unhealthful oddity of M. Guérin , ” then addressed him directly , saying , " we will see who emerges game and contuse from this match . ”
Guérin took the challenge literally : He launched himself at Pasteur and had to be physically restrained by the other researcher . The next day he denounced Pasteur as a prevaricator and demanded a affaire d’honneur .
What made this escalation even strange is that Pasteur was 59 and partly paralyzed from a stroke , and Guérin was 80 years old . Luckily the two old men never faced one another with side arm . Guérin back down after it became clear that Pasteur had the support of the Académie ’s board of theatre director .
Guérin ’s also arguedthat source play no part in infecting wounds . Luckily for us , the research of Pasteur , Joseph Lister , and others advance out , while Guérin has been mostly forgotten .
5. John Pitcairn, Jr. (1841-1916)
A Scotch immigrant to the U.S. , Pitcairn worked his way up from servitude to extreme riches , founding PPG Industriesand shaping the advanced - day oil and raw flatulency industries . When his son Raymond was immunise in 1885 , he experienced a minor infection ; this brief illness may have been induce by the vaccinum or may have been a co-occurrence . Either way , Pitcairn became a fervent anti - vaxxer , and used his riches to promote the effort .
He was a follower of Swedenborgianism , a Christian designation base on the mystic visions of a 17th - century philosopher that had an upswing in popularity in the United States during the 19th century . Other Swedenborgians includedJohnny Appleseed , Robert Frost , and Ralph Waldo Emerson . Although Swedenborg himself had n’t had much to say about medication , his followers quickly became associated with homeopathy , a belief that disease was not stimulate by germs but by spiritual disorder . Doctors and medicinal drug , therefore , should stop studying the strong-arm and or else rivet on thementaland even theological wellness of an mortal .
For Pitcairn , this approaching to disease meant that vaccines were morally reprehensible . He define inoculation as " the puttingof an impure affair into the descent . ” More than that , he think thatany strong-arm contaminationleft its Gospel According to Mark not only on the body but also on their immortal ego , and therefore inject someone with a vaccine was the same as deliberately mark their soul .
Pitcairn ’s veridical impingement come not his accurate belief , but from his pocketbook . In 1906 he organized the Pennsylvania Anti - Vaccination League ( of which he was made prexy for life),the first anti - vax organizationto have substantial money and living . But it did n’t succeed in repealing any vaccine mandate , and so in 1908 , Pitcairn helped to encounter the Anti - Vaccination League of America . Hewrote , “ We have repudiatedreligioustyranny ; we have rejectedpoliticaltyranny ; shall we now give in tomedicaltyranny ? " Despite being a millionaire himself , Pitcairn was also prompt to betoken the finger at the supposed pecuniary incentives of inoculator [ PDF ] : “ There is nomoneyin the causa we play ; it is the cause of truth , the cause of exemption , the drive of humanity ; but it is said that there are 20 million dollars invest in vaccinum farms in this country . ” Despite being appointed by the governor of Pennsylvania to a peculiar commission to investigate vaccinations , Pitcairn never did manage to change any laws .
After his dying , his son Harold and Raymond ( who had recovered from that infection ) continued to support the Anti - Vaccination League and similar causes , where they always stood up for liberty against government intervention — even fightingagainstlaws intended to terminate child labor .
6. Henning Jacobson (1856-1930)
A Lutheran rector and Swedish immigrant to Massachusetts , Jacobson probably never expected to become a famous name , but any law bookman — particularly one who ’s been paying attention to case over the last year and a half — will have heard of the Supreme Court decisionJacobson v. Massachusetts .
In 1899 , yet another smallpox epidemic strike Boston and the surrounding area . The Cambridge Board of Health responded by ordering all inhabitants of the city to be vaccinated . When the epidemicendedin 1903 , 270 people had choke — but 485,000 people ( about 83 percent of the city ) had been vaccinated , likely saving the lives of many . Jacobson was not one of them . He and his Logos refused to be vaccinated , and when the city set about to squeeze him , Jacobson took them to court .
start at the Middlesex County territory court , then the state supreme court , and finally the United States Supreme Court , Jacobson and his lawyer pleaded his instance that God , not vaccines , would protect him . One lawyer take , “ Can the barren citizen of Massachusetts , who is not yet a heathen , not an idolator , be compel to undergo this rite and to take part in this new — no , revised — form of worship of the Sacred Cow ? ”
The Supreme Court did n’t take theideathat vaccinum were " a barbarous ceremonial of roue - poisoning ” and moo-cow worship very badly . In a 7 - 2 ruling , they detect that the governance did have the right to impose mandatory vaccinum , because“real shore leave for all could not exist ” if person used their liberty to injure others .
7. Lora Little (1856-1931)
Little was born in a log cabin , but in many way her activities could fit aright in with the twenty-first - century world of Twitter and Instagram . She trust in the importance of whole wheat , brown Sir Tim Rice , and “ Hindu - Yogi ” breathing practice . She wrote a newspaper column titled “ Health in the Suburbs , ” advertised her avail as a health instructor , and go internationally togive lectureson how to " eat up right , be right . " Sheranfor the Oregon House of Representatives in 1913 — only one twelvemonth after women received full voting rights in that country .
Little was most famous , however , for her anti - vax drive . She was the editor ofThe Liberator , an anti - vax paper list after the famousantislaverypaper of the pre - Civil War era . Little’sLiberatorran for only five years , but was well - see by other anti - vaxxers as far away as Britain . In 1906 , she publishedCrimes of the Cowpox Ring : Some Moving Pictures Thrown on the Dead Wall of Official Science , which feed the profile of 336 “ victim ” of inoculation . Some of these deaths may indeed have been the outcome of vaccination ; in the day before antibiotic , without modern sterilization procedures , it was possible for the wound due to an shot to become septic , even fatally so . Other expiry , though obviously tragedies , have less of a connection . Little include her own son , Kenneth , in the inclination of vaccine end , though he diedof diphtheria eight months after receive a smallpox vaccination . It seems unlikely that the two consequence had anything to do with one another .
Like many today , Little believed in the curative power of nature and common sense . “ Trust nature , is a safe slogan than trust the doc , ” she compose . She argued against the “ artificial pollution ” of vaccines . On the other hand , she did n’t consider inanykind of medicament ; disease was not because of microbe , but by the body cleaning itself , concord to her . As long as you trace the right diet , find the correct exercise , and stayed unobjectionable , all your disease and trauma would " apace disappear . ” That ’s right : everything from tetanus to cancer cured by refreshing aura , garden play , and hop breakfast .
8. Joseph Pulitzer (1847-1911)
In addition to inventingyellow journalismand establish the Pulitzer Prizes , Joseph Pulitzerwas an former medium plugger of the antivax movement . In 1901 , he possess thePost - Dispatchnewspaper of St. Louis and saw his opportunity to deal paper when a inoculation scandal strike the city .
Diphtheria was a major killer of children in 1901 , and like today , antibody were used as a treatment to save lives . The antibody were produced by horses shoot with diphtheria toxin . Eventually , physicins could draw blood from the knight , extract the antibody , and come in them into suffering kid . This all work fairly well — except when horses were exposed to diseases other than diphtheria . In September 1901 , a horse named Jim had his diphtheria antibodies drawn , and shortly afterwards developed tetanus . His antibodies were supposed to be destruct , but due to a commixture - up , they were instead send out out to doctors across the city . The first youngster injected with Jim ’s antibodies was a young girl named Bessie Baker . She quickly go back from her tear of diphtheria , but died of lockjaw five days after receiving the barb . Thirteen childrenin St. Louis died from these contaminated injections , include both of Bessie ’s sib .
Pulitzerbegan writing attention - grabbing headlines that brought countrywide care to the tragedy . unluckily , only a few months later in October 1901 , tetanus contaminate a hatful of smallpox vaccine from cows by chance exposed to a tetanus - infected Equus caballus in Camden , New Jersey . This time11 children died . Again , Pulitzer turned tragedy into a money - making operation .
Ironically , due in enceinte part to Pulitzer ’s furtherance of the scandal , the very next yearPresidentTheodore Rooseveltsigned the Biologics Control Act . For the first time , the governance had the power to find out who was allowed to construct vaccine and to superintend quality mastery . This act allows the FDA to regulate vaccine today , and to verify that no accidents like the ones in St. Louis and Camden ever find again .